• Precision Therapies for Autoimmune Diseases

    By Sue De Pasquale

  • Transforming Treatment for Autoimmune Diseases

    Read about the promise of cellular therapies and our work in Breakthrough

  • Engineered T-cell Therapies to Treat Autoimmune Diseases

    We are excited to host an outstanding panel of speakers on precision cellular immunotherapies and CAR-Tregs at The American College of Rheumatology Symposium at FOCIS 2023!

  • CATCR-T cell therapy may aid in antiphospholipid syndrome through selective B-cell depletion

    Upcoming T-cell therapies may treat antiphospholipid syndrome and other autoimmune diseases without compromising a patient’s defenses against infection.

  • Learn about our precision immunotherapy work at #ACR22

    We introduce CATCR-T cells, a novel engineered T cell receptor technology to selectively target autoreactive B cells that drive autoimmune diseases (Plenary Session III, November 14, 2022).

  • Konig receives American College of Rheumatology Distinguished Fellow Award

  • Mutant Gene-Targeted Immunotherapy Approach Developed

    A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

  • Cancer Immunotherapy Approach Targets Common Genetic Alteration

    Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.

  • Increased Survival in Patients with Pneumonia Taking Alpha-1 Blockers at Baseline

    The benefit of alpha blockers may extend to other respiratory infection. Read more in eLife.

  • Alpha-1 Blockers are Associated with Increased Survival in COVID-19

    Retrospective data from the United States Department of Veterans Affairs suggests benefit of inhibiting catecholamine-mediated cytokine dysregulation to prevent severe COVID-19

  • Storm Cells

    Researchers at Johns Hopkins are racing to understand the connection between SARS-CoV-2 and a deadly immune system malfunction called a cytokine storm.

  • Credit: Getty Images

    Preventing Cytokine Storm May Ease COVID-19 Symptoms

    Read more on Forbes

  • Image Credit: www.MedicalGraphics.de (CC BY-ND 4.0)

    Researchers Urge Clinical Trial to Prevent Lethal Complication of COVID-19

    Read more on Johns Hopkins News

  • How RA Begins: A Detective Story

    Read more in LEAP Magazine

  • Aggregatibacter Actinomycetemcomitans May Be a Trigger for Rheumatoid Arthritis

    Read our interview on Healio Rheumatology

  • How a Periodontal Infection Might Trigger RA

    A pathogen linked to periodontal disease might trigger production of autoantigens that set off and sustain inflammatory immune responses in the joints in rheumatoid arthritis (RA).

  • doi:10.7295/W9CIL39044

    Linking Rheumatoid Arthritis and Gum Disease: Researchers Find Common Bacterium

    Researchers from Johns Hopkins Medicine have narrowed down the link between chronic gum disease and rheumatoid arthritis, identifying the common bacterium at play in both conditions.